Updates on hepatorenal syndrome and strategies bridging to liver transplantation
نویسندگان
چکیده
Hepatorenal syndrome is not an uncommon life-threatening complication arising from liver cirrhosis. The diagnostic criteria for this syndrome have been revised throughout the years, with recent revisions aimed at improving earlier diagnosis and treatment. Liver transplantation remains the only definitive treatment for hepatorenal syndrome. Due to the scarcity of liver grafts, many patients die waiting. This review focuses on the different strategies to bridge patients to liver transplantation and to improve the postoperative outcome.
منابع مشابه
Liver transplantation as ultimate tool to treat portal hypertension.
Portal hypertension is a complication of liver cirrhosis that may itself cause complications such as variceal bleeding, ascites and hepatorenal syndrome. There are several options for symptomatic treatment including drug therapy, endoscopy, transjugular intrahepatic portosystemic shunt (TIPS), and various surgical procedures, notably liver transplantation, the only causal treatment. The indicat...
متن کاملCombined Liver-Kidney Transplantation for Hepatorenal Syndrome
Among various complications of end-stage liver disease, hepatorenal syndrome has the highest mortality. Patients with both end-stage liver disease and end-stage renal disease are candidates for combined liver-kidney transplantation. However, patients with cirrhosis with decompensation presenting in the form of hepatorenal syndrome, are also likely candidates for the procedure. Herein, we presen...
متن کاملRenal Dysfunction in Patients with Chronic Liver Disease
Renal dysfunction in patients with chronic liver disease encompasses a clinical spectrum of hyponatremia, ascites, and hepatorenal syndrome. Clinical observation has suggested that patients with cirrhosis have hyperdynamic circulation, and recent studies strongly suggest that peripheral arterial vasodilatation and subsequent development of hyperdynamic circulation are responsible for disturbanc...
متن کاملThe reversal of the hepatorenal syndrome in four pediatric patients following successful orthotopic liver transplantation.
Four pediatric patients are presented in whom profound renal failure (hepatorenal syndrome) developed in association with severe end-stage liver disease. All four patients had successful orthotopic liver transplantation. Special emphasis is given to the preoperative and postoperative renal function in the patients, and the criteria used to establish the diagnosis of the hepatorenal syndrome are...
متن کاملHepatorenal Syndrome and Hyponatremia
• Hyponatremia and hepatorenal syndrome are complications that occur in patients with cirrhosis and ascites and represent a stage of “further” decompensation of cirrhosis • Worsened vasodilatation with consequent non-osmotic release of arginine-vasopressin and renal vasoconstriction are the main pathogenic mechanism for hyponatremia and hepatorenal syndrome, respectively • Both hyponatremia and...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2017